EMT inhibitor-2
Product Specifications
UNSPSC Description
EMT inhibitor-2 (Compound 1) inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes. EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively[1].
Target Antigen
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/emt-inhibitor-2.html
Purity
99.55
Solubility
DMSO : 83.33 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
COC1=C(O)C2=C(OC(C3=CC=C(OC)C(OC)=C3)=CC2=O)C=C1OCCN(C4)CCNC4=O
Molecular Weight
470.47
References & Citations
[1]Youn, Byung Soo, et al. Substituted chromenes for treatment of fibrosis or non-alcoholic steatohepatitis. US10370364.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128859/EMT-inhibitor-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128859/EMT-inhibitor-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2232228-60-1
Available Sizes
Curated Selection
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