2,6-Dichlorodiphenylamine

2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.

Product Specifications

CAS Number

[15307-93-4]

Product Name Alternative

2,6-Dichloro-N-phenylaniline

UNSPSC

12352005

Hazard Statement

H315, H319, H410

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/2-6-dichlorodiphenylamine.html

Purity

99.78

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=C(NC2=CC=CC=C2)C(Cl)=CC=C1

Molecular Formula

C12H9Cl2N

Molecular Weight

238.12

Precautions

H315, H319, H410

References & Citations

[1]Makoto Urai, et al. Potent Drugs That Attenuate anti-Candida Albicans Activity of Fluconazole and Their Possible Mechanisms of Action. J Infect Chemother. 2014 Oct;20 (10) :612-5.