Protosappanin B

Protosappanin B is a phenolic compound extracted from Caesalpinia sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].

Product Specifications

CAS Number

[102036-29-3]

Product Name Alternative

(-) -Protosappanin B

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protosappanin-b.html

Purity

99.46

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=CC=C2C(OC[C@@](O)(CO)CC3=CC(O)=C(O)C=C23)=C1

Molecular Formula

C16H16O6

Molecular Weight

304.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Yang X, et al. Antitumor Effects of Purified Protosappanin B Extracted From Lignum Sappan. Integr Cancer Ther. 2016 Mar;15 (1) :87-95.|[2]Yang X, et al. Protosappanin B promotes apoptosis and causes G1 cell cycle arrest in human bladder cancer cells. Sci Rep. 2019 Jan 31;9 (1) :1048.