Lu AF11205
Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors.
Product Specifications
CAS Number
1290133-16-2
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lu-af11205.html
Smiles
O=C(N1CCCCC1)C2=CN=C(S2)C#CC3=CC=CC=C3
Molecular Formula
C17H16N2OS
Molecular Weight
296.39
References & Citations
[1]Fused thiazolyl alkynes as potent mGlu5 receptor positive allosteric modulators
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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