M-AM-BBIQ
M-AM-BBIQ (compound 10) is a dual TLR7 and TLR8 agonist, with EC50 values of 0.12 μM and 1.7 μM for hTLR7 and hTLR8, respectively[1].
Product Specifications
CAS Number
[1258457-58-7]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/m-am-bbiq.html
Smiles
NC1=NC2=CC=CC=C2C3=C1N=C(CCCC)N3CC4=CC=CC(CN)=C4
Molecular Formula
C22H25N5
Molecular Weight
359.47
References & Citations
[1]Kushvinder Kumar, et al. Modulation of the Adjuvant Potential of Imidazoquinoline-Based TLR7/8 Agonists via Alum Adsorption. ACS Med. Chem. Lett. 2024, July. 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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