Ribonuclease T1, Aspergillus oryzae

Ribonulease T1, Aspergillus oryzae (Rnase T1), is commonly used in biochemical research. Ribonuclease T1 is an endonuclease that can specifically degrade single stranded RNA. Ribonuclease T1 can form nucleoside 2 ', 3 '-cyclic phosphoric acid intermediates to cut the phosphodiester bond between 3' -guanosine residues and adjacent nucleoside 5 '-OH groups to produce 3' -GMP terminal oligonucleotides[1].

Product Specifications

CAS Number

[9026-12-4]

Product Name Alternative

Rnase T1

UNSPSC

12352204

Target

DNA/RNA Synthesis

Type

Enzyme

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ribonulease-t1-aspergillus-oryzae.html

Solubility

H2O : ≥ 100 mg/mL

Smiles

[RibonucleaseT1,Aspergillusoryzae]

References & Citations

[1]Heinemann U, et al. Crystallographic study of mechanism of ribonuclease T1-catalysed specific RNA hydrolysis. J Biomol Struct Dyn. 1983 Oct;1 (2) :523-38.