Protoneogracillin

Protoneogracillin, a furostanol glycoside, shows anti-fungal activity against the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and cytotoxic activity on K562 cancer cells (IC50=6.6 μM) [1][2].

Product Specifications

CAS Number

[191334-50-6]

UNSPSC

12352005

Target

Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/protoneogracillin.html

Purity

99.96

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](C[C@@]3([H])[C@]2([H])[C@@H]([C@](O)(O3)CC[C@H](C)CO[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)([H])[C@@]5([H])[C@]([C@@]6(C(C[C@H](CC6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)=CC5)C)([H])CC1

Molecular Formula

C51H84O23

Molecular Weight

1065.20

References & Citations

[1]Hu K, et, al. Antineoplastic agents. II. Four furostanol glycosides from rhizomes of Dioscorea collettii var. hypoglauca. Planta Med. 1997 Apr;63 (2) :161-5.|[2]Liu HW, et, al. New furostanol glycosides from the rhizomes of Dioscorea futschauensis R. Kunth. J Asian Nat Prod Res. 2003 Dec;5 (4) :241-7.