(S, R) -LSN3318839
(S, R) -LSN3318839 is the stereoisomer of LSN3318839 (HY-142162) . LSN3318839 is an orally active positive modulator of the glucagon-like peptide-1 receptor (GLP-1R) . LSN3318839 can increase the secretion of insulin and has the effect of lowering blood sugar[1].
Product Specifications
CAS Number
[2765539-92-0]
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-r-lsn3318839.html
Purity
98.25
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@H](C1=CC=CC=C1C2=NC=C3N=CN(C3=C2)[C@@H](C4=C(C(C5CC5)=CC=C4Cl)Cl)C)C(O)=O
Molecular Formula
C26H23Cl2N3O2
Molecular Weight
480.39
References & Citations
[1]Willard FS, et al., Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor. J Med Chem. 2021 Mar 25;64 (6) :3439-3448.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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