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(S, R) -LSN3318839

(S, R) -LSN3318839 is the stereoisomer of LSN3318839 (HY-142162) . LSN3318839 is an orally active positive modulator of the glucagon-like peptide-1 receptor (GLP-1R) . LSN3318839 can increase the secretion of insulin and has the effect of lowering blood sugar[1].

Product Specifications

UNSPSC

12352005

Target

GCGR

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/s-r-lsn3318839.html

Purity

98.25

Solubility

DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@H](C1=CC=CC=C1C2=NC=C3N=CN(C3=C2)[C@@H](C4=C(C(C5CC5)=CC=C4Cl)Cl)C)C(O)=O

Molecular Formula

C26H23Cl2N3O2

Molecular Weight

480.39

References & Citations

[1]Willard FS, et al., Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor. J Med Chem. 2021 Mar 25;64 (6) :3439-3448.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-142162A/S-R-LSN3318839-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-142162A/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[2765539-92-0]

Available Sizes

Curated Selection

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