(S, R) -LSN3318839
(S, R) -LSN3318839 is the stereoisomer of LSN3318839 (HY-142162) . LSN3318839 is an orally active positive modulator of the glucagon-like peptide-1 receptor (GLP-1R) . LSN3318839 can increase the secretion of insulin and has the effect of lowering blood sugar[1].
Product Specifications
CAS Number
[2765539-92-0]
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-r-lsn3318839.html
Purity
98.25
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@H](C1=CC=CC=C1C2=NC=C3N=CN(C3=C2)[C@@H](C4=C(C(C5CC5)=CC=C4Cl)Cl)C)C(O)=O
Molecular Formula
C26H23Cl2N3O2
Molecular Weight
480.39
References & Citations
[1]Willard FS, et al., Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor. J Med Chem. 2021 Mar 25;64 (6) :3439-3448.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
251749-AP 100 µL
SLC36A2 (Solute Carrier Family 36 (Proton/amino Acid symporter), Member 2, FLJ16051, MGC119658, MGC119660, PAT2, TRAMD1) (AP) discontinued
Sign In for Pricing
View Details 
MBS6296430-01 0.2 mL
ERCC8, ID (ERCC8, CKN1, CSA, DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA) (Azide free) (HRP)
Sign In for Pricing
View Details 
MBS6296430-02 5x 0.2 mL
ERCC8, ID (ERCC8, CKN1, CSA, DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA) (Azide free) (HRP)
Sign In for Pricing
View Details 
GTR15348649 1 Vial
Lentiviral human CYBC1 shRNA (UAS) - Lentiviral human CYBC1 shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details FY-EM1732S 96 Well
Easypro Mouse S100 Calcium Binding Protein A11 (S100A11) ELISA Kit
Sign In for Pricing
View Details MBS9428421-01 96 Tests
Human RISC-loading complex subunit TARBP2 ELISA Kit
Sign In for Pricing
View Details