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Human Ephrin-B2 / EFNB2 Protein, Fc tag (MALS verified)

Selected Variant

EPN-H5259-500ug

Size: 500 µg

Ephrin-B2 (EFNB2) is also known as EPH-related receptor tyrosine kinase ligand 5 (LERK-5) or HTK ligand (HTK-L), which belongs to the ephrin family. The ephrin-B (ENFB) class are transmembrane proteins implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. EFNB2 has been shown to interact with EPHA3 and EPHB1 in optic chiasm development. EFNB2 has also been shown to serve as a receptor for Hendra Virus and Nipah Virus, mediating entry into the cell during infection.

Product Specifications

Background

Ephrin-B2 (EFNB2) is also known as EPH-related receptor tyrosine kinase ligand 5 (LERK-5) or HTK ligand (HTK-L), which belongs to the ephrin family. The ephrin-B (ENFB) class are transmembrane proteins implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. EFNB2 has been shown to interact with EPHA3 and EPHB1 in optic chiasm development. EFNB2 has also been shown to serve as a receptor for Hendra Virus and Nipah Virus, mediating entry into the cell during infection.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.8 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P52799-1

Expression Region

Ser 25 - Ala 168

Host

HEK293

Target

Ephrin-B2

Conjugation

Unconjugated

Tag

C-Fc

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Nipah virus Glycoprotein, His Tag (Cat. No. GLN-N52H3) at 5 μg/mL (100 μL/well) can bind Human Ephrin-B2 Protein, Fc tag (Cat. No. EPN-H5259) with a linear range of 0.1-2 ng/mL (QC tested).

Format

Powder

Buffer

50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5

Additives

Trehalose

Molecular Weight

42.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*1

Host or Source

HEK293

Species

Human

Protein ID

P52799-1

Preservative

Trehalose

Price

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