Anti-inflammatory agent 75
Anti-inflammatory agent 75 (Compound 14) is an α-pyrone derivative that can be isolated from the traditional medicinal plant St. John's Wort (Hypericum henryi.) . Anti-inflammatory agent 75 has anti-inflammatory activity, inhibiting the phosphorylation and degradation of NF-κB inhibitors, thereby suppressing the activation of NF-κB[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-75.html
Solubility
10 mM in DMSO
Smiles
CC1(C=CC(/C(O1)=C/C(C2=CC=CC=C2)=O)=O)C
Molecular Formula
C15H14O3
Molecular Weight
242.27
References & Citations
[1]Hu B, et al. Hyperhenrones: Prenylated α-pyrones with anti-inflammatory activity from Hypericum henryi. Phytochemistry. 2024 Jan 31;220:114007.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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