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Anti-inflammatory agent 75

Anti-inflammatory agent 75 (Compound 14) is an α-pyrone derivative that can be isolated from the traditional medicinal plant St. John's Wort (Hypericum henryi.) . Anti-inflammatory agent 75 has anti-inflammatory activity, inhibiting the phosphorylation and degradation of NF-κB inhibitors, thereby suppressing the activation of NF-κB[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-75.html

Solubility

10 mM in DMSO

Smiles

CC1(C=CC(/C(O1)=C/C(C2=CC=CC=C2)=O)=O)C

Molecular Formula

C15H14O3

Molecular Weight

242.27

References & Citations

[1]Hu B, et al. Hyperhenrones: Prenylated α-pyrones with anti-inflammatory activity from Hypericum henryi. Phytochemistry. 2024 Jan 31;220:114007.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

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