Sacubitril-d5 (hemicalcium)
Sacubitril-d5 (AHU-377-d5) hemicalcium is deuterium-labeled Sacubitril hemicalcium (HY-15407A) [1].
Product Specifications
Product Name Alternative
AHU-377-d5 (hemicalcium)
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Neprilysin
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C(CCC([O-])=O)N[C@H](CC1=CC=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C=C1)C[C@@H](C)C(OCC)=O.[0.5Ca2+]
Molecular Formula
C24H24D5NO5.1/2Ca
Molecular Weight
435.55
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Smith K A, et al. Soil and environmental analysis[M]. Marcel Dekker Incorporated, 2000.|[3]Fan T W M, et al. Stable isotope-resolved metabolomics and applications for drug development[J]. Pharmacology & therapeutics, 2012, 133 (3) : 366-391.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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