Bupranolol (hydrochloride)
Bupranolol hydrochloride is a non-selective β-adrenergic blocker with potent membrane stabilizing activity. Bupranolol hydrochloride is able to significantly modulate the contractile activity of the non-pregnant human uterus. Bupranolol hydrochloride showed significant effects on spontaneous uterine contractions in an in vitro study in patients with ovarian cancer. Bupranolol hydrochloride is similar in potency to propranolol, another β-adrenergic blocker. Bupranolol hydrochloride is rapidly and completely absorbed in vivo, and its major metabolite is carboxybupranolol[1].
Product Specifications
CAS Number
[15148-80-8]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bupranolol-hydrochloride.html
Smiles
OC(CNC(C)(C)C)COC1=CC(C)=CC=C1Cl.Cl
Molecular Formula
C14H23Cl2NO2
Molecular Weight
308.24
References & Citations
[1]Myometrial Responses to Beta-Adrenoceptor Antagonists in Gynecological Malignancies
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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