Amorolfine
Amorolfine (Ro 14-4767) is an antifungal agent. Amorolfine ameliorates the onychomycosis through inhibition of ergosterol biosynthesis. Amorolfine inhibits Candida albicans with a MIC of 0.404 µg/mL[1][2].
Product Specifications
CAS Number
78613-35-1
Product Name Alternative
Ro 14-4767; Ro 14-4767/000
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/amorolfine.html
Smiles
C[C@H]1O[C@H](CN(C1)CC(CC2=CC=C(C=C2)C(C)(CC)C)C)C
Molecular Formula
C21H35NO
Molecular Weight
317.51
References & Citations
[1]Pittrof F, et al., Loceryl nail lacquer--realization of a new galenical approach to onychomycosis therapy. Clin Exp Dermatol. 1992 Sep;17 Suppl 1:26-8.|[2]Haria M, et al. Amorolfine. A review of its pharmacological properties and therapeutic potential in the treatment of onychomycosis and other superficial fungal infections. Drugs. 1995 Jan;49 (1) :103-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
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