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KMT2C/ MLL3 Recombinant Rabbit Monoclonal Antibody [PSH02-11]

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Histone-lysine N-methyltransferase 2C EC:2.1.1.364 Lysine N-methyltransferase 2C Homologous to ALR protein Myeloid/lymphoid or mixed-lineage leukemia protein 3 KMT2C HALR KIAA1506 MLL3

Abbreviation

KMT2C, HALR, KIAA1506, MLL3

Swiss Prot

Q8NEZ4 Human, Q8BRH4 Mouse,

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse

Immunogen

Recombinant protein within human KMT2C aa 3,251-3,550 / 4,911.

Isotype

IgG

Clone

PSH02-11

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB

Positive Control

U-2 OS cell lysate, MCF7 cell lysate, HCT 116 cell lysate, rat skeletal muscle tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 541 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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