FLT3-IN-16-d1

FLT3-IN-16-d1 is the deuterium labeled FLT3-IN-16 (HY-148036) . FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].

Product Specifications

UNSPSC

12352005

Target

FLT3; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(C1=C(NC(C2=C([2H])C=CN=C2)=O)SC3=C1CCCC3)N

Molecular Formula

C15H14DN3O2S

Molecular Weight

302.37

References & Citations

[1]Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16 (12) :3282-6.