Deutenzalutamide
Deutenzalutamide (Enzalutamide-d3) is a developed deuterium labeled Enzalutamide (MDV3100) . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].
Product Specifications
CAS Number
[1443331-82-5]
Product Name Alternative
Enzalutamide-d3; MDV3100-d3; HC-1119
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Androgen Receptor; Autophagy
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.81
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(NC([2H])([2H])[2H])C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C)(C)C2=O)C=C1F
Molecular Formula
C21H13D3F4N4O2S
Molecular Weight
467.45
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Tran C, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009 May 8;324 (5928) :787-90.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
Phase 3
Available Sizes
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