H-cis-Hyp-OMe (hydrochloride)

Product Specifications

UNSPSC Description

H-cis-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-cis-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR

Target Antigen

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related;PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/h-cis-hyp-ome-hydrochloride.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1NC[C@@H](O)C1)OC.Cl

Molecular Weight

181.62

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W016429/H-cis-Hyp-OMe-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W016429/H-cis-Hyp-OMe-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

40126-30-5

Available Sizes

Curated Selection

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