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Z-Leu-Leu-Tyr-COCHO

Z-Leu-Leu-Tyr-COCHO is a potent chymotrypsin-like activity inhibitor with a Ki value of 3.0 nM[1].

Product Specifications

CAS Number

204649-66-1

UNSPSC

12352209

Target

Proteasome

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/z-leu-leu-tyr-cocho.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1C[C@@H](C(C=O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O

Molecular Formula

C30H39N3O7

Molecular Weight

553.65

References & Citations

[1]Lynas JF, et, al. Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl alpha-keto aldehydes (glyoxals) . Bioorg Med Chem Lett. 1998 Feb 17;8 (4) :373-8.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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