Niraxostat
Niraxostat (Y-700; Piraxostat) is an orally active xanthine oxidoreductase (XOR) inhibitor used in the study of hyperuricemia and other diseases in which XOR may be involved[1].
Product Specifications
CAS Number
206884-98-2
Product Name Alternative
Y-700; Piraxostat
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Xanthine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/niraxostat.html
Purity
98.54
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(C2=CC=C(OCC(C)(C)C)C(C#N)=C2)N=C1)O
Molecular Formula
C16H17N3O3
Molecular Weight
299.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Fukunari A, et al. Y-700 [1-[3-Cyano-4- (2,2-dimethylpropoxy) phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion. J Pharmacol Exp Ther. 2004 Nov;311 (2) :519-28.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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