Niraxostat

Niraxostat (Y-700; Piraxostat) is an orally active xanthine oxidoreductase (XOR) inhibitor used in the study of hyperuricemia and other diseases in which XOR may be involved[1].

Product Specifications

CAS Number

[206884-98-2]

Product Name Alternative

Y-700; Piraxostat

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/niraxostat.html

Purity

98.54

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

O=C(C1=CN(C2=CC=C(OCC(C)(C)C)C(C#N)=C2)N=C1)O

Molecular Formula

C16H17N3O3

Molecular Weight

299.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Fukunari A, et al. Y-700 [1-[3-Cyano-4- (2,2-dimethylpropoxy) phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion. J Pharmacol Exp Ther. 2004 Nov;311 (2) :519-28.