Maceneolignan H
Maceneolignan H (Compound 8) is a neolignane compound isolated from the arils of Myristica fragrans. Maceneolignan H is a selective CCR3 antagonist (EC50 = 1.4 μM) . Maceneolignan H has the potential for the research of allergic diseases[1].
Product Specifications
CAS Number
1314042-85-7
UNSPSC
12352005
Target
CCR
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/maceneolignan-h.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]([C@@H](C(C=C1)=CC(OC)=C1OC)OC(C)=O)OC(C(OC)=CC(CC=C)=C2)=C2OC
Molecular Formula
C24H30O7
Molecular Weight
430.49
References & Citations
[1]Morikawa T, et al. Neolignans from the Arils of Myristica fragrans as Potent Antagonists of CC Chemokine Receptor 3. J Nat Prod. 2016;79 (8) :2005-2013.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CCR3
Frequently Asked Questions
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