Miptenalimab

Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3) . Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II[1].

Product Specifications

CAS Number

[2249882-55-9]

Product Name Alternative

BI-754111

UNSPSC

12352203

Target

LAG-3

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/miptenalimab.html

Purity

98.81

Solubility

10 mM in DMSO

Smiles

[Miptenalimab]

Molecular Weight

(145.84 kDa)

References & Citations

[1]Zettl M, et al. Combination of two novel blocking antibodies, anti-PD-1 antibody ezabenlimab (BI 754091) and anti-LAG-3 antibody BI 754111, leads to increased immune cell responses. Oncoimmunology. 2022 Jun 16;11 (1) :2080328.