Alagebrium chloride
Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor.
Product Specifications
CAS Number
341028-37-3
Product Name Alternative
ALT711
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Alagebrium_chloride.html
Concentration
10mM
Purity
99.82
Solubility
DMSO : ≥ 25 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=C1)C[N+]2=CSC(C)=C2C.[Cl-]
Molecular Formula
C13H14ClNOS
Molecular Weight
267.78
Precautions
H302, H315, H319, H335
References & Citations
[1]Watson AM, et al. Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGEactivation in diabetic apolipoprotein E knockout mice. Diabetes. 2012 Aug;61 (8) :2105-13.|[2]Wang H, et al. Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. Am J Physiol Heart Circ Physiol. 2015 Oct;309 (7) :H1130-40.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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