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NOD2 agonist 3

NOD2 agonist 3 (Compound 5) is a potent NOD2 agonist, with an EC50 of 111.45 nM. NOD2 agonist 3 shows immunopotentiating effects[1].

Product Specifications

CAS Number

[2289702-58-3]

UNSPSC

12352005

Target

NOD-like Receptor (NLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nod2-agonist-3.html

Smiles

COC1=C(O)C=CC(/C=C/C(NCC(N[C@H](C(N[C@H](CCC(OCC)=O)C(OCC)=O)=O)C(C)C)=O)=O)=C1

Molecular Formula

C26H37N3O9

Molecular Weight

535.59

References & Citations

[1]Janež Š, et al. Linker Chemistry and Connectivity Fine-Tune the Immune Response and Kinetic Solubility of Conjugated NOD2/TLR7 Agonists. Bioconjug Chem. 2024 Oct 10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NOD2

Curated Selection

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