Sulfo DBCO-PEG4-Maleimide (TEA)
Product Specifications
UNSPSC Description
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sulfo-dbco-peg4-maleimide-tea.html
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1C=CC(N1CCC(NCCOCCOCCOCCOCCC(NCC(S(=O)(O)=O)C(NCCC(N2C3=C(C#CC4=C(C2)C=CC=C4)C=CC=C3)=O)=O)=O)=O)=O.CCN(CC)CC
Molecular Weight
927.07
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140307A/Sulfo-DBCO-PEG4-Maleimide-TEA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140307A/Sulfo-DBCO-PEG4-Maleimide-TEA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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