Oxytocin-neurophysin 1 / OXT Recombinant Rabbit Monoclonal Antibody [PSH08-24]
Selected Variant
HA722968
Size: 100 µL
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth. Oxytocin is released into the bloodstream as a hormone in response to sexual activity and during childbirth. It is also available in pharmaceutical form. In either form, oxytocin stimulates uterine contractions to speed up the process of childbirth. In its natural form, it also plays a role in maternal bonding and milk production. Production and secretion of oxytocin is controlled by a positive feedback mechanism, where its initial release stimulates production and release of further oxytocin. For example, when oxytocin is released during a contraction of the uterus at the start of childbirth, this stimulates production and release of more oxytocin and an increase in the intensity and frequency of contractions. This process compounds in intensity and frequency and continues until the triggering activity ceases. A similar process takes place during lactation and during sexual activity.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Oxytocin-neurophysin 1, OT-NPI, Oxytocin, Ocytocin, Neurophysin 1, OXT, OT
Swiss Prot
P01178 Human, P35454 Mouse,
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human OXT aa 1-125.
Isotype
IgG
Clone
PSH08-24
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IHC-Fr, IF-Tissue
Positive Control
Concentration
0.2 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:2,000-1:5,000 ;IHC-Fr: 1;500 ;IF-Tissue: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 13 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
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