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Oxytocin-neurophysin 1 / OXT Recombinant Rabbit Monoclonal Antibody [PSH08-24]

Selected Variant

HA722968

Size: 100 µL

Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth. Oxytocin is released into the bloodstream as a hormone in response to sexual activity and during childbirth. It is also available in pharmaceutical form. In either form, oxytocin stimulates uterine contractions to speed up the process of childbirth. In its natural form, it also plays a role in maternal bonding and milk production. Production and secretion of oxytocin is controlled by a positive feedback mechanism, where its initial release stimulates production and release of further oxytocin. For example, when oxytocin is released during a contraction of the uterus at the start of childbirth, this stimulates production and release of more oxytocin and an increase in the intensity and frequency of contractions. This process compounds in intensity and frequency and continues until the triggering activity ceases. A similar process takes place during lactation and during sexual activity.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

MGC126890 antibody MGC126892 antibody Neurophysin 1 antibody Neurophysin I antibody Ocytocin antibody OT antibody OT NPI antibody OXT antibody Oxytocin antibody Oxytocin Neurophysin preproprotein antibody Oxytocin prepro (neurophysin I) antibody Oxytocin prepropeptide antibody Oxytocin-neurophysin 1 antibody

Abbreviation

Oxytocin-neurophysin 1, OT-NPI, Oxytocin, Ocytocin, Neurophysin 1, OXT, OT

Swiss Prot

P01178 Human, P35454 Mouse,

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human OXT aa 1-125.

Isotype

IgG

Clone

PSH08-24

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IHC-Fr, IF-Tissue

Positive Control

Mouse paraventricular nucleus tissue, rat supraoptic nucleus tissue, mouse pituitary tissue, rat pituitary tissue, Mouse pituitary tissue lysate, Rat pituitary tissue lysate.

Concentration

0.2 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:2,000-1:5,000 ;IHC-Fr: 1;500 ;IF-Tissue: 1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 13 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Price

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