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Cadherin-6/KCAD, Human (HEK293, Fc)

Cadherin-6/KCAD Protein, Human (HEK293, Fc), a recombinant human Cadherin-6 produced in HEK293 cells, has an Fc fragment at the C-terminus. Cadherin-6 (CDH6) is a type 2 cadherin, which drives epithelial cells toward a mesenchymal condition (EMT) during embryonic development and it is aberrantly re-activated in cancer[1].

Product Specifications

Product Name Alternative

Cadherin-6/KCAD Protein, Human (HEK293, Fc), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/cadherin-6-kcad-protein-human-hek293-fc.html

Smiles

TLSTPLSKRTSGFPAKKRALELSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGA-Fc

Molecular Formula

1004 (Gene_ID) P55285-1 (T19-A615) (Accession)

Molecular Weight

Approximately 110-130 kDa, based on SDS-PAGE under reducing conditions.

References & Citations

[1]M Gugnoni, et al. Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy. Oncogene. 2017 Feb 2;36 (5) :667-677.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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