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Nilutamide (Standard)

Nilutamide (Standard) is the analytical standard of Nilutamide. This product is intended for research and analytical applications. Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties[1][4].

Product Specifications

CAS Number

63612-50-0

Product Name Alternative

Nilandron (Standard) ; RU 23908 (Standard)

UNSPSC

12352005

Target

Androgen Receptor; Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Infection; Endocrinology

Assay Protocol

https://www.medchemexpress.com/nilutamide-standard.html

Smiles

O=C1N(C2=CC=C([N+]([O-])=O)C(C(F)(F)F)=C2)C(C(C)(C)N1)=O

Molecular Formula

C12H10F3N3O4

Molecular Weight

317.22

References & Citations

[1]Harris MG, et al. Nilutamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer. Drugs Aging. 1993 Jan-Feb;3 (1) :9-25.|[2]Babany G, et al. Inhibitory effects of nilutamide, a new androgen receptor antagonist, on mouse and human liver cytochrome P-450. Biochem Pharmacol. 1989 Mar 15;38 (6) :941-7.|[3]Simard J, et al. Comparison of in vitro effects of the pure antiandrogens OH-flutamide, Casodex, and nilutamide on androgen-sensitive parameters. Urology. 1997 Apr;49 (4) :580-6; discussion 586-9.|[4]Keiser J, Vargas M, Vennerstrom JL. Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice. J Antimicrob Chemother. 2010 Sep;65 (9) :1991-5.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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