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NW-1689

NW-1689 is a process-related impurity of safinamide mesilate (SAFM) . SAFM is a drug used to treat Parkinson's disease (PD) . It is a highly selective and reversible inhibitor of monoamine oxidase-B (MAO-B) and also blocks sodium channels and N-type calcium channels. These effects of SAFM help reduce the breakdown of dopamine and inhibit the release of glutamate. NW-1689 has a similar chemical structure to SAFM and has some similar pharmacological effects as SAFM, and can be used in Parkinson's disease research[1].

Product Specifications

CAS Number

405-85-6

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nw-1689.html

Smiles

C1=CC(=CC(=C1)F)COC2=CC=C(C=C2)C(=O)O

Molecular Formula

C14H11FO3

Molecular Weight

246.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Zou L, et al. Identification, characterization, and quantification of impurities of safinamide mesilate: process-related impurities and degradation products[J]. Journal of AOAC International, 2017, 100 (4) : 1029-1037.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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