KIN1148
KIN1148, a small-molecule IRF3 agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy.
Product Specifications
CAS Number
[1428729-56-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/KIN1148.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=NC2=CC=C3C(N=CS3)=C2S1)C4=CC5=C(C=C4)C=CC=C5
Molecular Formula
C19H11N3OS2
Molecular Weight
361.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Probst P, et al. A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response. Vaccine. 2017 Apr 4;35 (15) :1964-1971.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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