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Flupentixol (dihydrochloride) (Standard)

Flupentixol (dihydrochloride) (Standard) is the analytical standard of Flupentixol (dihydrochloride) . This product is intended for research and analytical applications. Flupentixol is an orally active D1/D2 dopamine receptor antagonist and new PI3K inhibitor (PI3Kα IC50=127 nM) . Flupentixol shows anti-proliferative activity to cancer cells and induces apoptosis. Flupentixol can also be used in schizophrenia, anxiolytic and depressive research[1][2][3].

Product Specifications

CAS Number

2413-38-9

Product Name Alternative

Flupenthixol (dihydrochloride) (Standard)

UNSPSC

12352005

Target

Apoptosis; Dopamine Receptor; PI3K; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; GPCR/G Protein; Neuronal Signaling; Others; PI3K/Akt/mTOR

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/flupentixol-dihydrochloride-standard.html

Smiles

OCCN1CCN(CC/C=C2C3=C(SC4=C/2C=CC=C4)C=CC(C(F)(F)F)=C3)CC1.[H]Cl.[H]Cl

Molecular Formula

C23H27Cl2F3N2OS

Molecular Weight

507.44

References & Citations

[1]Yonar D, et al. Effect of cis- (Z) -flupentixol on DPPC membranes in the presence and absence of cholesterol. Chem Phys Lipids. 2016 Jun;198:61-71.|[2]Ruhrmann S, et al. Efficacy of flupentixol and risperidone in chronic schizophrenia with predominantly negative symptoms. Prog Neuropsychopharmacol Biol Psychiatry. 2007 Jun 30;31 (5) :1012-22.|[3]Chao Dong, et al. The antipsychotic agent flupentixol is a new PI3K inhibitor and potential anticancer drug for lung cancer. Int J Biol Sci. 2019 Jun 2;15 (7) :1523-1532.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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