XTT (sodium hydrate)

XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.

Product Specifications

CAS Number

[413585-64-5]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/xtt-sodium-hydrate.html

Smiles

O=C(C1=NN([N+](C2=C(OC)C=C([N+]([O-])=O)C(S(=O)([O-])=O)=C2)=N1)C3=C(OC)C=C([N+]([O-])=O)C(S(=O)(O[Na])=O)=C3)NC4=CC=CC=C4.O.[x]

Molecular Formula

C22H17N7O13S2.xH2O.Na

References & Citations

[1]Sutherland, et al. The tetrazolium dyes MTS and XTT provide new quantitative assays for superoxide and superoxide dismutase. Free Radic. Res. 27 (3), 283-289 (1997) .