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(R) -HH2853

(R) -HH2853 is a mutant EZH2 inhibitor with an IC50 of EZH2-Y641F. (R) -HH2853 can be used for cancer and autoimmune diseases (WO2018045971A1; compound 201) [1].

Product Specifications

CAS Number

2202678-06-4

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/r-hh2853.html

Solubility

10 mM in DMSO

Smiles

C[C@@H](N1CCN(CC1)CC(F)(F)F)C2=C(C)C(C(NCC3=C(C=C(NC3=O)C)OC)=O)=CC4=C(C5=CC=C(N=N5)C)C=CN24

Molecular Formula

C31H36F3N7O3

Molecular Weight

611.66

References & Citations

[1]Xuxing Chen, et al. Pyrido five-element aromatic ring compound, preparation method therefor and use thereof. WO2018045971A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EZH2

Available Sizes

Frequently Asked Questions

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