(R) -HH2853
(R) -HH2853 is a mutant EZH2 inhibitor with an IC50 of EZH2-Y641F. (R) -HH2853 can be used for cancer and autoimmune diseases (WO2018045971A1; compound 201) [1].
Product Specifications
CAS Number
2202678-06-4
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-hh2853.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](N1CCN(CC1)CC(F)(F)F)C2=C(C)C(C(NCC3=C(C=C(NC3=O)C)OC)=O)=CC4=C(C5=CC=C(N=N5)C)C=CN24
Molecular Formula
C31H36F3N7O3
Molecular Weight
611.66
References & Citations
[1]Xuxing Chen, et al. Pyrido five-element aromatic ring compound, preparation method therefor and use thereof. WO2018045971A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EZH2
Available Sizes
Frequently Asked Questions
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