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M122

M122 is a potent inhibitor of HDAC1 and HDAC2, with the IC50 values of 0.48 μM and 0.47 μM, respectively, respectively. M122 has antitumor activity[1].

Product Specifications

CAS Number

2127411-50-9

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m122.html

Smiles

S=C(N1CCN(C2=CC=NC=C2)CC1)SCC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3

Molecular Formula

C24H25N5OS2

Molecular Weight

463.62

References & Citations

[1]Rui Xie, et al. Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents. Eur J Med Chem. 2018 Jan 1:143:320-333.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC2

Frequently Asked Questions

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