M122
Product Specifications
UNSPSC Description
M122 is a potent inhibitor of HDAC1 and HDAC2, with the IC50 values of 0.48 μM and 0.47 μM, respectively, respectively. M122 has antitumor activity[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m122.html
Smiles
S=C(N1CCN(C2=CC=NC=C2)CC1)SCC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3
Molecular Weight
463.62
References & Citations
[1]Rui Xie, et al. Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents. Eur J Med Chem. 2018 Jan 1:143:320-333.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125645/M122-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125645/
Clinical Information
No Development Reported
CAS Number
2127411-50-9
Curated Selection
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