M122
M122 is a potent inhibitor of HDAC1 and HDAC2, with the IC50 values of 0.48 μM and 0.47 μM, respectively, respectively. M122 has antitumor activity[1].
Product Specifications
CAS Number
[2127411-50-9]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m122.html
Smiles
S=C(N1CCN(C2=CC=NC=C2)CC1)SCC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3
Molecular Formula
C24H25N5OS2
Molecular Weight
463.62
References & Citations
[1]Rui Xie, et al. Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents. Eur J Med Chem. 2018 Jan 1:143:320-333.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2
Curated Selection
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