MPDC (hydrochloride)
MPDC hydrochloride is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes[1].
Product Specifications
UNSPSC
12352005
Target
GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mpdc-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1[C@@]2([H])[C@@H](C(O)=O)[C@@]2([H])CN1)O.[H]Cl
Molecular Formula
C7H10ClNO4
Molecular Weight
207.61
References & Citations
[1]Bridges RJ, et al. A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine dicarboxylate. Neurosci Lett. 1994 Jun 20;174 (2) :193-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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