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GPR88 agonist 2

GPR88 agonist 2 (compound 53) is a potent and brain-penetrantGPR88 agonist with an EC50 value of 14 µM in GPR88 cAMP functional assay[1].

Product Specifications

CAS Number

2821859-71-4

UNSPSC

12352005

Target

GPR88

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Others

Assay Protocol

https://www.medchemexpress.com/gpr88-agonist-2.html

Purity

99.57

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CNC(C(N=N1)=CN1C[C@@H](C2=CC=C(C=C2)OC[C@@H](C)CC)NC([C@H](C3=CC=CC=C3)C)=O)=O

Molecular Formula

C26H33N5O3

Molecular Weight

463.57

References & Citations

[1]Rahman MT, et al. Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies. J Med Chem. 2021 Aug 26;64 (16) :12397-12413.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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