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FGFR-1, Rhesus Macaque (HEK293, His)

FGFR-1 protein is a tyrosine-protein kinase that acts as a cell surface receptor for fibroblast growth factor and plays a critical role in the complex regulation of embryonic development, cell proliferation, differentiation, and migration. FGFR-1 mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1, MAP kinase signaling pathways, and AKT1 signaling pathways. FGFR-1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived FGFR-1 protein, expressed by HEK293 , with C-His labeled tag.

Product Specifications

Product Name Alternative

FGFR-1 Protein, Rhesus Macaque (HEK293, His), Rhesus Macaque, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/fgfr1-protein-rhesus-macaque-hek293-his.html

Purity

98.0

Smiles

RPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLY

Molecular Formula

700126 (Gene_ID) H9FRD4/NP_001253576.1 (R22-Y283) (Accession)

Molecular Weight

Approximately 50-75 kDa due to the glycosylation.

References & Citations

[1]Katoh M, et al. FGF receptors: cancer biology and therapeutics. Med Res Rev. 2014 Mar;34 (2) :280-300.|[2]Kelleher FC, et al. Fibroblast growth factor receptors, developmental corruption and malignant disease. Carcinogenesis. 2013 Oct;34 (10) :2198-205.|[3]Mariz BALA, et al. Expression of FGF-2/FGFR-1 in normal mucosa, salivary gland, preneoplastic, and neoplastic lesions of the oral cavity. J Oral Pathol Med. 2018 Oct;47 (9) :816-822.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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