N-Desmethylolanzapine

N-Desmethylolanzapine is an antipsychotic drug. The formation of N-Desmethylolanzapine correlates with the level and activity of human liver flavin-containing monooxygenase (FMO3) . N-Desmethylolanzapine can be used in the study of antipsychotic drugs [1].

Product Specifications

CAS Number

[161696-76-0]

Product Name Alternative

N-Demethylolanzapine; LY170055

UNSPSC

12352005

Hazard Statement

H225, H302, H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-desmethylolanzapine.html

Purity

98.0

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CC(S1)=CC2=C1NC3=CC=CC=C3N=C2N4CCNCC4

Molecular Formula

C16H18N4S

Molecular Weight

298.42

Precautions

H225, H302, H319

References & Citations

[1]Ring BJ, et al. Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther. 1996 Feb;276 (2) :658-66.