Human CD38 Protein, His Tag (MALS verified)
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Product Specifications
Background
Specifications
Accession Number
NP_001766
Expression Region
Val 43 - Ile 300
Host
HEK293
Target
CD38
Conjugation
Unconjugated
Tag
C-6xHis
Source
Human
Stability
Endotoxin
0.2 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
50 mM MES, 100 mM NaCl, pH6.5
Additives
Trehalose
Molecular Weight
30.7 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
HEK293
Species
Human
Protein ID
NP_001766
Preservative
Trehalose
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