5-Hydroxypyrazine-2-Carboxylic Acid
5-Hydroxypyrazine-2-Carboxylic Acid, a metabolite of anti-tuberculosis drug pyrazinamide (PZA) .
Product Specifications
CAS Number
[34604-60-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-hydroxypyrazine-2-carboxylic-acid.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 4 mg/mL (ultrasonic)
Smiles
O=C(O)C1=NC=C(O)N=C1
Molecular Formula
C5H4N2O3
Molecular Weight
140.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Huq, Fazlul; Hossain, Zahed. Molecular modelling analysis of the metabolism of pyrazinamide. Journal of Pharmacology and Toxicology (2006), 1 (6), 505-515.|[2]Mehmedagic, Aida; Verite, Philippe; Menager, Sabine et al. Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats. Biopharmaceutics & Drug Disposition (2002), 23 (5), 191-195.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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