5-Hydroxypyrazine-2-Carboxylic Acid

5-Hydroxypyrazine-2-Carboxylic Acid, a metabolite of anti-tuberculosis drug pyrazinamide (PZA) .

Product Specifications

CAS Number

[34604-60-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-hydroxypyrazine-2-carboxylic-acid.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 4 mg/mL (ultrasonic)

Smiles

O=C(O)C1=NC=C(O)N=C1

Molecular Formula

C5H4N2O3

Molecular Weight

140.10

Precautions

H302, H315, H319, H335

References & Citations

[1]Huq, Fazlul; Hossain, Zahed. Molecular modelling analysis of the metabolism of pyrazinamide. Journal of Pharmacology and Toxicology (2006), 1 (6), 505-515.|[2]Mehmedagic, Aida; Verite, Philippe; Menager, Sabine et al. Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats. Biopharmaceutics & Drug Disposition (2002), 23 (5), 191-195.