Salvigenin-d9

Product Specifications

UNSPSC Description

Salvigenin-d9 is the deuterium labeled Salvigenin. Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties[1][2].

Target Antigen

Autophagy

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C2=CC=C(OC([2H])([2H])[2H])C=C2)OC3=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C(O)=C13

Molecular Weight

337.37

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Rafatian G, et al. Increase of autophagy and attenuation of apoptosis by Salvigenin promote survival of SH-SY5Y cells following treatment with H₂O₂. Mol Cell Biochem. 2012 Dec;371(1-2):9-22.|[3]Noori S, et al. Antitumor and immunomodulatory effects of salvigenin on tumor bearing mice. Cell Immunol. 2013 Nov-Dec;286(1-2):16-21.