(-) -Blebbistatin
(-) -Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II[1][2].
Product Specifications
CAS Number
856925-71-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Myosin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/_-_-Blebbistatin.html
Purity
99.42
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
CC1=CC=C(N=C(N(C2=CC=CC=C2)CC3)[C@]3(O)C4=O)C4=C1
Molecular Formula
C18H16N2O2
Molecular Weight
292.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Cristina Lucas‐Lopez, et al. Absolute Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool, (–) ‐Blebbistatin.|[2]Ponsaerts R, et al. The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellularcalcium wave propagation in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2008 Nov;49 (11) :4816-27.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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