JQ-1 (carboxylic acid) -NH-C2-NH-COOH
Selected Variant
HY-169082
Size: 1 Each
JQ-1 (carboxylic acid) -NH-C2-NH-COOH is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates), which is composed of JQ-1 carboxylic acid and the corresponding linker: (2-Aminoethyl) carbamic acid (HY-W398806). JQ-1 (carboxylic acid) -NH-C2-NH-COOH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jq-1-carboxylic-acid-nh-c2-nh-cooh.html
Smiles
O=C(O)NCCNC(C[C@@H]1N=C(C2=C(N3C(C)=NN=C13)SC(C)=C2C)C4=CC=C(C=C4)Cl)=O
Molecular Formula
C22H23ClN6O3S
Molecular Weight
486.97
References & Citations
[1]Qian Shao, et al. "Targeted Protein Localization by Covalent 14–3–3 Recruitment." Journal of the American Chemical Society (2024) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Bcl-6 (Follicular Lymphoma Marker) (BCL6/1526), CF405S conjugate, 0.1mg/mL
PD1, Mouse (RMP1-14), CF568 conjugate, 0.1mg/mL
NSE gamma (Neuron Specific Enolase, gamma) (Neuroendocrine Marker) (NSE-P2), CF647 conjugate, 0.1mg/mL
Anti-Phospholipase A2/PLA2G4A Antibody Picoband®, Cy3 Conjugate
