Anti-Hu CD123 PerCP
CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha) . This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
Product Specifications
Certification
RUO
Immunogen
IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
Target Antigen
CD123
Clone
6H6
Applications
FC (QC tested)
Format
PerCP
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgG1
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